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Deep learning models have demonstrated impressive accuracy in predicting acute kidney injury (AKI), a condition affecting up to 20% of ICU patients, yet their black-box nature prevents clinical adoption in high-stakes critical care settings. While existing interpretability methods like SHAP, LIME, and attention mechanisms can identify important features, they fail to capture the temporal dynamics essential for clinical decision-making, and are unable to communicate when specific risk factors become critical in a patient's trajectory. This limitation is particularly problematic in the ICU, where the timing of interventions can significantly impact patient outcomes. We present a novel interpretable framework that brings temporal awareness to deep learning predictions for AKI. Our approach introduces three key innovations: (1) a latent convolutional concept bottleneck that learns clinically meaningful patterns from ICU time-series without requiring manual concept annotation, leveraging Conv1D layers to capture localized temporal patterns like sudden physiological changes; (2) Temporal Concept Tracing (TCT), a gradient-based method that identifies not only which risk factors matter but precisely when they become critical addressing the fundamental question of temporal relevance missing from current XAI techniques; and (3) integration with MedAlpaca to generate structured, time-aware clinical explanations that translate model insights into actionable bedside guidance. We evaluate our framework on MIMIC-IV data, demonstrating that our approach performs better than existing explainability frameworks, Occlusion and LIME, in terms of the comprehensiveness score, sufficiency score, and processing time. The proposed method also better captures risk factors inflection points for patients timelines compared to conventional concept bottleneck methods, including dense layer and attention mechanism. This work represents the first comprehensive solution for interpretable temporal deep learning in critical care that addresses both the what and when of clinical risk factors. By making AKI predictions transparent and temporally contextualized, our framework bridges the gap between model accuracy and clinical utility, offering a path toward trustworthy AI deployment in time-sensitive healthcare settings.more » « lessFree, publicly-accessible full text available November 23, 2026
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Free, publicly-accessible full text available May 1, 2026
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Free, publicly-accessible full text available July 1, 2026
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Online reviews play a crucial role in influencing seller–customer dynamics. This research evaluates the credibility and consistency of reviews based on volume, length, and content to understand the impacts of incentives on customer review behaviors, how to improve review quality, and decision-making in purchases. The data analysis reveals major factors such as costs, support, usability, and product features that may influence the impact. The analysis also highlights the indirect impact of company size, the direct impact of user experience, and the varying impacts of changing conditions over the years on the volume of incentive reviews. This study uses methodologies such as Sentence-BERT (SBERT), TF-IDF, spectral clustering, t-SNE, A/B testing, hypothesis testing, and bootstrap distribution to investigate how semantic variances in reviews could be used for personalized shopping experiences. It reveals that incentive reviews have minimal to no impact on purchasing decisions, which is consistent with the credibility and consistency analysis in terms of volume, length, and content. The negligible impact of incentive reviews on purchase decisions underscores the importance of authentic online feedback. This research clarifies how review characteristics sway consumer choices and provides strategic insights for businesses to enhance their review mechanisms and customer engagement.more » « less
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PurposeThis study aims to evaluate a method of building a biomedical knowledge graph (KG). Design/methodology/approachThis research first constructs a COVID-19 KG on the COVID-19 Open Research Data Set, covering information over six categories (i.e. disease, drug, gene, species, therapy and symptom). The construction used open-source tools to extract entities, relations and triples. Then, the COVID-19 KG is evaluated on three data-quality dimensions: correctness, relatedness and comprehensiveness, using a semiautomatic approach. Finally, this study assesses the application of the KG by building a question answering (Q&A) system. Five queries regarding COVID-19 genomes, symptoms, transmissions and therapeutics were submitted to the system and the results were analyzed. FindingsWith current extraction tools, the quality of the KG is moderate and difficult to improve, unless more efforts are made to improve the tools for entity extraction, relation extraction and others. This study finds that comprehensiveness and relatedness positively correlate with the data size. Furthermore, the results indicate the performances of the Q&A systems built on the larger-scale KGs are better than the smaller ones for most queries, proving the importance of relatedness and comprehensiveness to ensure the usefulness of the KG. Originality/valueThe KG construction process, data-quality-based and application-based evaluations discussed in this paper provide valuable references for KG researchers and practitioners to build high-quality domain-specific knowledge discovery systems.more » « less
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